Head-to-head
LillyDirect (Zepbound) vs HealthRX: GLP-1 Prices Compared
Released: Last reviewed:
On October 15, 2026, LillyDirect (Zepbound)’s all-in price at the maintenance dose averages $486 a month and HealthRX’s $214, so HealthRX costs $272 less a month on average; HealthRX costs $3,269 less over a year of month-to-month billing ($2,568 vs $5,837).
Only prices read on the providers’ own pages on October 15, 2026 produce a verdict here; older records are shown with their dates and are not compared. Confirm the total at checkout.
Tirzepatide: LillyDirect (Zepbound) vs HealthRX
| LillyDirect (Zepbound) | HealthRX | |
|---|---|---|
| All-in monthly at maintenance | $486/mo ($449 per 4 weeks) | $214/mo |
| Cheapest 12-month route, per month | $486/mo | $179/mo |
| 12-month cost | $5,837 | $2,148 |
| Membership / program fee | None | None |
| Dose pricing | By dose: $299 (2.5 mg), $399 (5 mg), $449 (7.5-15 mg) when each refill is bought within 45 days; otherwise $499 (7.5 mg) and $699 (10-15 mg) | Flat ('one flat plan price') |
| Status | Verified · 2026-10-15 | Verified · 2026-10-15 |
The arithmetic
On October 15, 2026, LillyDirect (Zepbound)’s all-in price at the maintenance dose averages $486 a month and HealthRX’s $214, so HealthRX costs $272 less a month on average; HealthRX costs $3,269 less over a year of month-to-month billing ($2,568 vs $5,837).
Semaglutide: LillyDirect (Zepbound) vs HealthRX
| LillyDirect (Zepbound) | HealthRX | |
|---|---|---|
| All-in monthly at maintenance | Not offered | $165/mo |
| Cheapest 12-month route, per month | Not offered | $99/mo |
| 12-month cost | Not offered | $1,188 |
| Membership / program fee | Not offered | None |
| Dose pricing | Not offered | Flat ('one flat plan price') |
| Status | Not offered | Verified · 2026-10-15 |
The arithmetic
No like-for-like semaglutide verdict: LillyDirect (Zepbound) does not offer semaglutide.
Terms side by side
LillyDirect (Zepbound)
- BillingNo subscription; self-pay per fill; Lilly defines a month as 28 days
- PharmacyLillyDirect self-pay pharmacy channel
HealthRX
- BillingMonthly plan ($239 listed, renews at $214; or $99 first month then $214), or 3-, 6- and 12-month plans prepaid ($627 / $1,194 / $2,148)
- CancellationYou can cancel anytime by emailing support@healthrx.com.
- Pharmacyus-licensed section 503a compounding pharmacy (not named)
Questions people ask
Is LillyDirect (Zepbound) or HealthRX cheaper for tirzepatide?
On October 15, 2026, LillyDirect (Zepbound)’s all-in price at the maintenance dose averages $486 a month and HealthRX’s $214, so HealthRX costs $272 less a month on average; HealthRX costs $3,269 less over a year of month-to-month billing ($2,568 vs $5,837). Both figures are all-in monthly prices at the maintenance dose, including any membership fee.
What does a year of tirzepatide cost at LillyDirect (Zepbound) and HealthRX?
Using each program’s cheapest published 12-month route as read on October 15, 2026: $5,837 at LillyDirect (Zepbound) and $2,148 at HealthRX. Prepaid plans lower the monthly price but raise what you lose if you stop early, so read the refund terms first.
Are compounded GLP-1s from either program FDA-approved?
No compounded tirzepatide or semaglutide is FDA-approved, and neither is a generic version of Zepbound, Mounjaro, Wegovy or Ozempic. Brand products sold by LillyDirect and NovoCare are FDA-approved. Ask which pharmacy fills your prescription and check its state license.
What will checkout show that this page does not?
Taxes, state availability, current promotions and any change made after our read date. Screenshot the order summary before you pay; that screen, not a comparison page, shows what you are agreeing to.
Records: LillyDirect (Zepbound) · HealthRX · price database · downloads. Official sites: LillyDirect (Zepbound) ↗ · HealthRX ↗.