Head-to-head
OrderlyMeds vs PlexusDx: GLP-1 Prices Compared
Released: Last reviewed:
On October 15, 2026, OrderlyMeds’s all-in price at the maintenance dose averages $299 a month and PlexusDx’s $189, so PlexusDx costs $110 less a month on average; PlexusDx costs $1,320 less over a year of month-to-month billing ($2,268 vs $3,588).
Only prices read on the providers’ own pages on October 15, 2026 produce a verdict here; older records are shown with their dates and are not compared. Confirm the total at checkout.
Tirzepatide: OrderlyMeds vs PlexusDx
| OrderlyMeds | PlexusDx | |
|---|---|---|
| All-in monthly at maintenance | $299/mo | $189/mo |
| Cheapest 12-month route, per month | $299/mo | $129/mo |
| 12-month cost | $3,588 | $1,548 |
| Membership / program fee | None | None |
| Dose pricing | Flat across doses (stated) | Flat ('Your price won't' go up with dose) |
| Status | Verified · 2026-10-15 | Verified · 2026-10-15 |
The arithmetic
On October 15, 2026, OrderlyMeds’s all-in price at the maintenance dose averages $299 a month and PlexusDx’s $189, so PlexusDx costs $110 less a month on average; PlexusDx costs $1,320 less over a year of month-to-month billing ($2,268 vs $3,588).
Semaglutide: OrderlyMeds vs PlexusDx
| OrderlyMeds | PlexusDx | |
|---|---|---|
| All-in monthly at maintenance | $149/mo | $149/mo |
| Cheapest 12-month route, per month | $149/mo | $99/mo |
| 12-month cost | $1,788 | $1,188 |
| Membership / program fee | None | None |
| Dose pricing | Flat across doses (stated) | Flat (dose increases do not change price) |
| Status | Verified · 2026-10-15 | Verified · 2026-10-15 |
The arithmetic
Both list semaglutide at $149 a month at the maintenance dose (read October 15, 2026), so price does not separate them; billing terms and what is included do.
Terms side by side
OrderlyMeds
- Billing2-month starter paid up front ($299 for 2 months), then the standard monthly rate
- CancellationWhen you sign up, you can cancel any time before the doctor finalizes your prescription, unless you've selected a multi-month plan.
- PharmacyWe currently partner with PerfectRx/PerfectionRx, ProRx, Casa, Pharmacy Hub and SmartPharmaRx. (All our pharmacy partners are 503A designated.)
PlexusDx
- BillingMonthly, or 3-, 6- and 12-month plans billed up front ($507 / $894 / $1,548)
- Cancellation3-, 6- and 12-month plans are charged once, up front, and renew automatically. Cancel future renewals anytime.
- Pharmacylicensed 503A compounding pharmacy (not named)
Questions people ask
Is OrderlyMeds or PlexusDx cheaper for tirzepatide?
On October 15, 2026, OrderlyMeds’s all-in price at the maintenance dose averages $299 a month and PlexusDx’s $189, so PlexusDx costs $110 less a month on average; PlexusDx costs $1,320 less over a year of month-to-month billing ($2,268 vs $3,588). Both figures are all-in monthly prices at the maintenance dose, including any membership fee.
What does a year of tirzepatide cost at OrderlyMeds and PlexusDx?
Using each program’s cheapest published 12-month route as read on October 15, 2026: $3,588 at OrderlyMeds and $1,548 at PlexusDx. Prepaid plans lower the monthly price but raise what you lose if you stop early, so read the refund terms first.
Is OrderlyMeds or PlexusDx cheaper for semaglutide?
Both list semaglutide at $149 a month at the maintenance dose (read October 15, 2026), so price does not separate them; billing terms and what is included do. Both figures are all-in monthly prices at the maintenance dose, including any membership fee.
What does a year of semaglutide cost at OrderlyMeds and PlexusDx?
Using each program’s cheapest published 12-month route as read on October 15, 2026: $1,788 at OrderlyMeds and $1,188 at PlexusDx. Prepaid plans lower the monthly price but raise what you lose if you stop early, so read the refund terms first.
Are compounded GLP-1s from either program FDA-approved?
No compounded tirzepatide or semaglutide is FDA-approved, and neither is a generic version of Zepbound, Mounjaro, Wegovy or Ozempic. Brand products sold by LillyDirect and NovoCare are FDA-approved. Ask which pharmacy fills your prescription and check its state license.
What will checkout show that this page does not?
Taxes, state availability, current promotions and any change made after our read date. Screenshot the order summary before you pay; that screen, not a comparison page, shows what you are agreeing to.
Records: OrderlyMeds · PlexusDx · price database · downloads. Official sites: OrderlyMeds ↗ · PlexusDx ↗.